Patients should really comprehend risks of lifetime-threatening respiratory despair and when this chance is greatest; clients should be knowledgeable that a genetic mutation could bring about greater codeine toxicity in a few patients; breastfed infants of ladies who definitely have this genetic mutation can also be in danger.

Studies in Women of all ages breastfeeding have shown unsafe infant results. An alternative choice to this medication needs to be prescribed or you should halt breastfeeding even though making use of this drugs.

Use with caution in people with underlying intestinal motility Diseases. The codeine in Promethazine with Codeine Oral Solution may possibly bring about spasm on the sphincter of Oddi, leading to an increase in biliary tract stress. Opioids could induce raises in serum amylase [seeWARNINGS AND PRECAUTIONS (5.21)]. Monitor individuals with biliary tract ailment, like acute pancreatitis for worsening signs and symptoms. Administration of promethazine has become linked with noted cholestatic jaundice.

Promethazine could decrease seizure threshold. It ought to be made use of with warning in persons with seizure Conditions or in individuals who're utilizing concomitant drugs, like narcotics or local anesthetics, which can also have an impact on seizure threshold.

This medication could comprise sugar and/or Liquor. Warning is encouraged When you have diabetic issues, Liquor dependence, or liver illness. Ask your medical professional or pharmacist about employing this merchandise safely and securely.

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It really is soluble in h2o and freely soluble in alcohol. It's a molecular excess weight of 320.88, a molecular system of C17H20N2S•HCI, and the subsequent structural components:

The phosphate salt of codeine happens as white, needle-shaped crystals or white crystalline powder. Codeine phosphate is freely soluble in h2o and a little bit soluble in Liquor. The molecular bodyweight is 406.37. Its molecular formulation is C18H21NO3•H3PO4 • ½ H2O, and it's got the next chemical construction.

Codeine has superior antitussive activity, Despite the fact that fewer than that of morphine at equivalent doses. It's used in preference to morphine, due to the fact side effects are infrequent at the usual antitussive dose of codeine.

Tend not to flush down a toilet or pour down a drain Except you are advised to take action. Verify with your pharmacist When you have questions on The obvious way to throw out drugs. here There might be drug get-back systems in your town. Client Info Use and Disclaimer

Will not get two doses at the same time or more doses. Persistently Promethazine VC/Codeine (promethazine, phenylephrine, and codeine) is taken on an as wanted basis. Will not just take more typically than explained to because of the medical doctor.

Ensure that you know how you respond to this medication before you decide to push, use machines, or do the rest which could be perilous if You aren't alert .

This medication may make the skin much more delicate to sunlight. Utilize a sunscreen when you are outside. Stay away from sunlamps and tanning beds .